Competitive intelligence
CI feed
Conference abstracts + payer decisions interleaved chronologically — the CI team aims to publish a structured briefing within 48 hours of any high-relevance event landing here.
16 items in window · 16 high-relevance
- Congresshighembargo lifts in 1dJun 1, 2026, 4:00 PMReal-world effectiveness of Kisqali vs standard of care in HR+ breast cancerMedian OS 33.8 months. HR 0.8 (95% CI 0.71–0.89). No new safety signals identified.Kisqali () · NovartisHR+ breast cancerMONALEESA-38 · NCT60056504Poster Discussion SessionOS33.8 monthsHR 0.8 (0.71-0.89)PFS22.8 monthsHR 0.77 (0.69-0.86)ORR77.9 percent
- Congresshighembargo lifts in 1dJun 1, 2026, 4:15 PMReal-world effectiveness of Enhertu vs standard of care in NSCLCMedian OS 29.4 months. HR 0.85 (95% CI 0.76–0.94). Grade ≥3 AEs consistent with prior reports.Enhertu () · Daiichi SankyoNSCLCDESTINY-Breast-376 · NCT30918589Poster SessionOS29.4 monthsHR 0.85 (0.76-0.94)PFS7.2 monthsHR 0.89 (0.8-0.91)ORR50.6 percent
- Congresshighembargo lifts in 2dJun 2, 2026, 3:45 PMLong-term follow-up of Ibrance 1L for HR+ breast cancer: PALOMA-349Median OS 37.6 months. HR 0.68 (95% CI 0.56–0.8). No new safety signals identified.Ibrance () · PfizerHR+ breast cancerPALOMA-349 · NCT90598054Oral Abstract SessionOS37.6 monthsHR 0.68 (0.56-0.8)PFS23.6 monthsHR 0.67 (0.53-0.78)ORR78 percent
- Congresshighembargo lifts in 2dJun 2, 2026, 4:00 PMBiomarker subgroup analysis of Tagrisso in NSCLC (the FLAURA-312 study)Median OS 28.5 months. HR 0.68 (95% CI 0.55–0.81). Grade ≥3 AEs consistent with prior reports.Tagrisso () · AstraZenecaNSCLCFLAURA-312 · NCT74476517Rapid Oral Abstract SessionOS28.5 monthsHR 0.68 (0.55-0.81)PFS8.8 monthsHR 0.69 (0.54-0.82)ORR44.2 percent
- Congresshighembargo lifts in 2dJun 2, 2026, 8:30 PMQuality of life outcomes with Kisqali in patients with HR+ breast cancerMedian OS 35.6 months. HR 0.7 (95% CI 0.62–0.78). Grade ≥3 AEs consistent with prior reports.Kisqali () · NovartisHR+ breast cancerMONALEESA-190 · NCT77693036Poster SessionOS35.6 monthsHR 0.7 (0.62-0.78)PFS20.5 monthsHR 0.74 (0.66-0.81)ORR55.5 percent
- Congresshighembargo lifts in 3dJun 3, 2026, 3:30 PMFLAURA-898: Tagrisso (osimertinib) 2L in NSCLCMedian OS 22.5 months. HR 0.76 (95% CI 0.66–0.86). Grade ≥3 AEs consistent with prior reports.Tagrisso () · AstraZenecaNSCLCFLAURA-898 · NCT65454622Poster SessionOS22.5 monthsHR 0.76 (0.66-0.86)PFS10.5 monthsHR 0.76 (0.68-0.84)ORR59.6 percent
- Congresshighembargo lifts in 3dJun 3, 2026, 3:45 PMBiomarker subgroup analysis of Verzenio in HR+ breast cancer (the MONARCH-410 study)Median OS 36.7 months. HR 0.9 (95% CI 0.77–0.99). No new safety signals identified.Verzenio () · Eli LillyHR+ breast cancerMONARCH-410 · NCT12503018Oral Abstract SessionOS36.7 monthsHR 0.9 (0.77-0.99)PFS22.3 monthsHR 0.93 (0.8-0.99)ORR58.8 percent
- Congresshighembargo lifts in 4dJun 4, 2026, 2:00 PMLong-term follow-up of Opdivo 3L+ for NSCLC: CheckMate-881Median OS 29.3 months. HR 0.6 (95% CI 0.51–0.69). No new safety signals identified.Opdivo () · Bristol-Myers SquibbNSCLCCheckMate-881 · NCT08001951Poster SessionOS29.3 monthsHR 0.6 (0.51-0.69)PFS7.4 monthsHR 0.61 (0.51-0.72)ORR60 percent
- Congresshighembargo lifts in 4dJun 4, 2026, 4:30 PMImfinzi plus chemotherapy in previously untreated biliary tract: updated analysis from PACIFIC-190Median OS 12.7 months. HR 0.83 (95% CI 0.72–0.94). Grade ≥3 AEs consistent with prior reports.Imfinzi () · AstraZenecabiliary tractPACIFIC-190 · NCT97449766Poster SessionOS12.7 monthsHR 0.83 (0.72-0.94)PFS7.5 monthsHR 0.83 (0.69-0.97)ORR34.7 percent
- Congresshighembargo lifts in 4dJun 4, 2026, 5:00 PMKeytruda plus chemotherapy in previously untreated NSCLC: updated analysis from KEYNOTE-645Median OS 22.4 months. HR 0.6 (95% CI 0.5–0.7). Grade ≥3 AEs consistent with prior reports.Keytruda () · MerckNSCLCKEYNOTE-645 · NCT22264892Poster Discussion SessionOS22.4 monthsHR 0.6 (0.5-0.7)PFS7.7 monthsHR 0.64 (0.49-0.67)ORR45.7 percent
- Congresshighembargo lifts in 4dJun 4, 2026, 7:45 PMQuality of life outcomes with Keytruda in patients with NSCLCMedian OS 25.6 months. HR 0.79 (95% CI 0.7–0.88). Grade ≥3 AEs consistent with prior reports.Keytruda () · MerckNSCLCKEYNOTE-433 · NCT65945184Poster SessionOS25.6 monthsHR 0.79 (0.7-0.88)PFS11.7 monthsHR 0.77 (0.66-0.89)ORR61.9 percent
- Congresshighembargo lifts in 5dJun 5, 2026, 2:15 PMQuality of life outcomes with Ibrance in patients with HR+ breast cancerMedian OS 38.2 months. HR 0.9 (95% CI 0.8–0.99). No new safety signals identified.Ibrance () · PfizerHR+ breast cancerPALOMA-223 · NCT98838794Oral Abstract SessionOS38.2 monthsHR 0.9 (0.8-0.99)PFS27.1 monthsHR 0.86 (0.8-0.95)ORR57.2 percent
- Congresshighembargo lifts in 5dJun 5, 2026, 5:00 PMReal-world effectiveness of Verzenio vs standard of care in HR+ breast cancerMedian OS 38.9 months. HR 0.58 (95% CI 0.47–0.69). No new safety signals identified.Verzenio () · Eli LillyHR+ breast cancerMONARCH-149 · NCT32526973Oral Abstract SessionOS38.9 monthsHR 0.58 (0.47-0.69)PFS19.4 monthsHR 0.6 (0.48-0.7)ORR74.7 percent
- Congresshighembargo lifts in 5dJun 5, 2026, 5:30 PMBiomarker subgroup analysis of Imfinzi in SCLC (the PACIFIC-419 study)Median OS 14.9 months. HR 0.83 (95% CI 0.74–0.92). No new safety signals identified.Imfinzi () · AstraZenecaSCLCPACIFIC-419 · NCT88358487Oral Abstract SessionOS14.9 monthsHR 0.83 (0.74-0.92)PFS6.1 monthsHR 0.81 (0.76-0.89)ORR63 percent
- Congresshighembargo lifts in 5dJun 5, 2026, 9:30 PMMONARCH-789: Verzenio (abemaciclib) neoadjuvant in HR+ breast cancerMedian OS 37.2 months. HR 0.87 (95% CI 0.75–0.99). No new safety signals identified.Verzenio () · Eli LillyHR+ breast cancerMONARCH-789 · NCT81284428Rapid Oral Abstract SessionOS37.2 monthsHR 0.87 (0.75-0.99)PFS24.7 monthsHR 0.85 (0.74-0.99)ORR58.8 percent
- Congresshighembargo lifts in 5dJun 5, 2026, 10:00 PMLong-term follow-up of Tecentriq maintenance for TNBC: IMpower-449Median OS 23.5 months. HR 0.86 (95% CI 0.75–0.97). No new safety signals identified.Tecentriq () · RocheTNBCIMpower-449 · NCT18767167Poster SessionOS23.5 monthsHR 0.86 (0.75-0.97)PFS9.9 monthsHR 0.87 (0.73-0.98)ORR50.8 percent